I have been following this thread and hesitated to jump in because I don't want to start any arguments.
Brief background, I raced mine from '97 till '13 when I wrecked it and am still rebuilding slowly.
I am not, and have never been, a 'professional wrench' but rather a pretty fair mechanic and wanting to understand systems & how they work is what made me a car guy originally. In the years I was racing I learned a lot about SU carbs.
Steve is right - you need real data to know what is going on and I started using an air/fuel monitor about 2001 but it took several years of still melting pistons and other problems before I did more research on air/fuel monitors and found that the inexpensive 1 wire meters are not very useful (sorry Steve). What you need is an analog wideband gage copy & paste this (I don't know how to do links
https://www.jegs.com/i/AEM/017/30-5130/10002/-1 this is Jegs but Summit & Amazon & others sell them. They are not cheap but will tell you an actual number as opposed to the one wire gages that show a row of led lights and a general rich/lean. And as Steve says, you need two, one for each downtube.
I encourage all of you to do your own research - this will give you the data the rolling roads give you. It is also what modern fuel injected cars use for input into the computer engine management.
So, I went a step further in 2009 because I was tired of going lean at 5500-6000 and not being able to correct it so I bought two of the above wide band air/fuel ratio gages and also bought an aircraft EGT gage that is made for 6 cylinder aircraft engines so I could have a probe in each header branch to know the temps of each cylinder - model I bought is Aerospace Logic EGT-100-6P & I purchased it from Gulf Coast Avionics (was $575 in 2009). With this you have a choice of showing one cylinder, having it cycle thru them all at about 2-3 seconds on each, or have it constantly scan and show the hottest. So now I can not only monitor air/fuel but also what that does in terms of EGT. Saved me several melted pistons/distorted valves. I now generate most of what a rolling road does just with out HP & Torque info.
I have found that if you change anything in your motor: cam, compression ratio, flow characteristics, etc. you will be off in fuel mix if you stick with the stock needles.
I don't have a rolling road anywhere near me so this is my DIY method.
I started with the bonnet off and measuring rods in the tops of the SUs (See Des Hamill, "How to power tune SUs" for making measuring rods). Then, with a helper - go for a drive and determine where the measuring rods are at any given rpm under full throttle up to wherever your red-line may be - for me that is 6000. Once you know where the pistons are at any given full throttle rpm, you also know where in the needle you are.... then if you show lean (by the wide band air/fuel) at say 3500 rpm, you can figure where on the needle you need to shave a bit to richen it up. At the same time I watch the EGTs to make sure I am not over cooking.
Side note here on EGTs - all my questioning around race tracks almost no one could ever tell me what is the max EGT before damage - the best consensus I got from several old timers is 1250-1300*F is about tops before damaging (a couple guys suggested 1500 should be ok?)- not sure that is true but I have tried to stay below 1300F. This leads me to Stoichiometric, which is about 14.7:1 if I recall correctly - in my case if I set to 14.7:1 the EGTs went thru the roof and I have found that I need to be around 10:1 in order to keep the EGTs down under 1300F. Again, this is under full throttle.
So, once again I will stress I am not a pro, and your mileage may vary - I have only done this with my engine which is .060 over 9.25:1 compression, headers, triple HD6, 283 degree cam (at 0 lift) but not particularly high lift and considerable flow effort on the head. I now make my own needles whenever I change anything - I know it is a bit of overkill and if your motor is stock I wouldn't go thru all this, I would just tune as the manual says.
As you can imagine, I can go on for days about this s**t but after a while my head hurts....
Dave