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David, She is a different dog! She has become very active and the other day my wife said that she saw Muffin run a short burst for the first time in 3 years! It appears that she is seemingly on a learning experience, almost like being reborn, it's amazing! I can't walk out of the room now unless she's on my heels, it was all worth the effort. She now has 7 bottles of eye drops, 6 are administered every day, some once a day and some twice a day, one twice a week, hopefully the vet will take her off some of them, but I think she'll be on some for quite a while. She is very good about getting her drops, which makes it much easier on me. Thanks for caring Dave, very much appreciated.