Assuming you set your valve clearance regularly, wear will only have the affect of slightly reduced oil to the front rockers on the shaft. Since it's already worn...the reduced oil may speed further shaft wear slightly.
I have noted that the steel rocker shaft wears much faster than the bronze rocker bushings. I have never figured that one out?!? Also, if you think about it, as the rockers rise with shaft wear, the valves will also be slowly rising with gradual valve seat wear. So...in the end they will keep the designed tappet to valve geometry. I really don't think rocker shaft wear will hurt anything, so long as you adjust the valve clearance to keep up with the wear.