I am in the process of building a TR6 engine. I'm using an Isky Z-19 cam, triple Strombergs/cold air box, header. Compression will be in the area of 9.5-1 with the head ported and polished. It is bored 30 over, with the rods lightened, Everything will be balanced along with the lightened flywheel. I figure to get in the area of what you want.
If you purchase Kas Kastner's Competition Manuals and Roger Williams, "How to Improve Triumph TR5, 250 & 6", you should have most of the information in hand to lead you to making the decisions toward what you want.
Good luck.