The early chassis with the fiberglass wrapped around the frane tubes were set up for eventual failure, it just took a few years. When I restored my Mk 3 Grantura, I cut the body off the frame, replaced all the missing/rotten frame tubes and fabricated new tunnels out of FG so that the body would socket over the frame, as well as mounting plates welded across the frame junctions so that bolts could be passed through the body and frame plates for mounting - a good way to ensure the serious rusting never recurred and also to enable easy demounting of the body if necessary in future.
It was a lot of work but had to be done and I itched for weeks. The car became a track car and AFAIK is still racing in the UK. So rust in those tubes does entail a lot of work to restore but shouldn't require a replacement frame.
If you contemplate a 'body wrap' car I'd recommend that small squares of glass be cut out with a Dremel or wheel so that the chassis tubes can be examined, but I'd also anticipate that on any car that saw much street use, the restoration as I outlined it will likely be necessary.