It very much depends on how they are influenced from birth, onward. Some can be great companions, others ferocious adversaries. They have personalities, no two the same. Overall behavior, yes, they are predatory animals but that instinct usually comes out only with provocation.
Keeping a tiger in a home begs for trouble.
Personally, I consider de-clawing any cat as inhumane. All ours were taught to use a scratching post, Merlyn taught this last one himself: when she was first introduced to the household and went to scratch the couch the first time, he went over to her and thwapped her on the head, then went and did an extended session at the post. She understood it and used the post from then to now. Ten years.
Another learned behavior she picked up on was vocalization. She was never heard to make a sound when she was outdoors, first five years of her life. After she'd become an indoor cat along with her sibling, Nimrod and The Lord of the Manor, Merlyn, she was thought to be mute. After a couple years' worth of Merlyn voicing different "words" (he truly did have 'vocabulary' of sorts-- his 'food word' was an "OWWA" noise, distinct from other utterances), she started making small vocal responses. Now at sixteen, she will mumble and respond to 'conversation'. Nothing as distinct or situation related as Merlyn's but vocal well beyond anything she did in the first five or seven years of her life. Positively "chatty" now.