The second picture looks like the natural color of the moon, when it is high in the sky. Orangeish when it's closer to the horizon near sun set. The last two look closest to a good exposure. The last one with the lower ISO seems to have less noise.
The focus looks just a tad soft but not bad. I don't know if you're using manual focus, but if not, do. If your camera can zoom in (like x5 or x10) on the rear viewfinder, I find it helpful to zoom in as much as I can and manually focus to get the sharpest looking zoomed in image (don't worry if it doesn't look super sharp zoomed in, just try to get it as sharp as you can. The real unzoomed image will then be sharper. I guarantee you that the perfect focus will not be at infinity, but a little bit closer than infinity. Also, you might try backing off the zoom. A lot of zoom lenses get less sharp when they are zoomed in all the way. For exam please, if your using a 200mm try taking a picture at 200, then back off to maybe 180 or 190. My Sigma 150-600 lens is decidedly sharper at 580 than it is all the way out to 600.