Although I have only done this on my 1500 Midget with the engine out of the car, I'm pretty sure that you can replace the center and rear main with the engine in the car. There's really nothing blocking the rear main cap when the oil pan is off. The "trick" might be pushing the upper bearing halves out, but it's "do-able". An aquaintance of mine claims that the front main can be changed with the engine "in-car" too. It may be possible, if you can remove the front pully, and then the two horizontal bolts that thread into the "filler plate" above the front main cap (you may even be able to get those two bolts out with the pulley in place, but it would be slow going). If you can get that filler cap out, the front main cap would be removeable.
Always a good idea to use "Plasti-Gage" when you do something like this (to be sure that the clearances are reasonable).
Whatever else, be absolutely *sure* to replace the thrust washers (they're on the center main only).....these things are a weak point in the BL 1500 engine....many of the 1500s I've seen have them sitting in oil pan when the pan is removed.